New study advances treatment options for PTSD
Dr Stephen Maren of Texas A&M University, recently published significant research on the psychological and neural basis of post-traumatic stress disorder (PTSD).
Maren's study looked at the areas of the brain that regulate emotion, including ceasing fear once danger has passed. Other factors, such as stress, can cause extinguished emotions of fear to relapse, which poses an issue for those with PTSD. He examined the neurons in the brain that cause fear relapse, and the influence of stress on these fear-reducing regions of the brain. The data reveals new insight into the pathophysiology of PTSD, and may be able to help predict and prevent fear relapse with treatments that reduce the effects of stress on the brain.
"The work shows that stress increases the activity of fear-promoting regions of the prefrontal cortex, while at the same time reducing activity in neighbouring fear-reducing regions," Maren said. "This shift in brain activity could be mimicked by increasing the activity of neurons that release the fight-or-flight neurotransmitter, norepinephrine. This finding paves the way for new treatments that reduce fear and its relapse after therapy."
More details on the report can be found here